Cyclooxygenase-2 Expression in Macrophages: Modulation by Protein Kinase C-a
نویسندگان
چکیده
منابع مشابه
Cyclooxygenase-2 expression in macrophages: modulation by protein kinase C-alpha.
Cyclooxygenase-2 (COX-2) is an inducible enzyme responsible for high levels of PG production during inflammation and immune responses. Previous studies with pharmacological inhibitors suggested a role for protein kinase C (PKC) in PG production possibly by regulating COX-2 expression. In this study, we addressed the role of PKC-alpha in the modulation of COX-2 expression and PGE2 synthesis by t...
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تاریخ انتشار 2000